It’s one thing to rule them all and another thing to bind them
نویسندگان
چکیده
منابع مشابه
One to rule them all
The development of transposon-based genome manipulation tools can benefit greatly from understanding transposons' inherent regulatory mechanisms. The Tc1-mariner transposons, which are being widely used in biotechnological applications, are subject to a self-inhibitory mechanism whereby increasing transposase expression beyond a certain point decreases the rate of transposition. In a recent pap...
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More than 60 years ago, the McGill University professor Donald Hebb published his famous postulate stating that to store a memory trace, the connection from a neuron that persistently helps activate another one should be strengthened (Hebb, 1949). Inspired by Hebb’s postulate, Rosenblatt (1958) a decade later introduced the perceptron learning machine as a simplified model of information storag...
متن کاملOne Query to Bind Them All
Recently, SPARQL became the standard language for querying RDF data on the Web. Like other formal query languages, it applies a Boolean-match semantics, i.e. results adhere strictly to the query. Thus, queries formulated for one dataset can not easily be reused for querying other datasets. If another target dataset is to be queried, the queries need to be rewritten using the vocabulary of the t...
متن کاملOne Binder to Bind Them All
High quality binders, such as antibodies, are of critical importance for chemical sensing applications. With synthetic alternatives, such as molecularly imprinted polymers (MIPs), less sensor development time and higher stability of the binder can be achieved. In this feature paper, I will discuss the impact of synthetic binders from an industrial perspective and I will challenge the molecular ...
متن کاملOne thing leads to another.
In 1956, the JCI published an article by Vincent Dole on a method for titrating plasma fatty acids that uncovered the importance of fatty acids as a substrate for glucose metabolism. When asked to prepare a historical perspective on this very popular paper, I paid Dole a visit and we reminisced. His answer to my question of how he came to do this work on plasma fatty acids was: "Well, one thing...
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ژورنال
عنوان ژورنال: Synthese
سال: 2018
ISSN: 0039-7857,1573-0964
DOI: 10.1007/s11229-018-01983-z